Lecture 'The epigenetics of inflammation & innate immune memory'

For whom
Employees , Students
When
08-12-2022 from 16:00 to 17:30
Where
Campus UZ Gent - Auditorium A (1K3) or livestream via MS Teams, Corneel Heymanslaan 10, 9000 Gent
Language
English
Organizer
Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences
Contact
kim.dekeyser@ugent.be
Website
https://www.ugent.be/ge/en/research/interdisciplinary-medicine-health-seminars.htm

This lecture will focus on the molecular mechanismes underlying the transcriptional programmes of subsets of immune genes in inflammatory responses.

This lecture is part of the Interdisciplinary Medical & Health Seminars

Guest speaker: Dr. Musa Mhlanga (Radboud Institute for Molecular Life Sciences, Radboud University - Radboud UMC, The Netherlands)

The biphasic nature of a healthy inflammatory response consists of successive waves of coordinated immune gene activation and attenuation (Bhatt et al. 2012). Complex genetic programmes orchestrate the coordinated transcription of subsets of immune genes, allowing for cycles of pro-inflammation and anti-inflammation to ensue (Medzhitov 2008, Rogatsky and Adelman 2014). However, the molecular mechanisms that underlie these transcriptional programmes remain poorly understood.

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